Juvenile nasopharyngeal angiofibromas (JNA) are a rare benign but locally aggressive vascular tumor. Epidemiology Juvenile nasopharyngeal angiofibromas. Introduction: Juvenile nasopharyngeal angiofibroma (NAJ) is a tumor with .. Acessos Cirúrgicos no Angiofibroma Nasofaríngeo Juvenil – Relato de caso e. Juvenile nasopharyngeal angiofibroma (JNA) is a rare and benign but locally aggressive fibrovascular tumor arising from the posterolateral wall of the.

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Service chief medical residency in Otorhinolaryngology, Universidade Federal de Sergipe. Modern imaging and its influence on the surgical treatment of juvenile angiofibroma.

Diagnosis of JNA is made by complete history, clinical examination, radiography, nasal endoscopy and by using specialized imaging techniques such as arteriography, computer tomography and magnetic resonance imaging. By using this site, you agree to the Terms of Use and Privacy Policy. Juvenile nasopharyngeal angiofibromas are benign but highly vascular tumours. Of our 20 patients, only 2 underwent surgery without clamping of the external carotid arteries, with both showing more bleeding than the 18 who underwent surgery with clamping.

Avid enhancement is noted on contrast-enhanced CT. Tumors that further extend into the infratemporal fossa may progress into the orbit, through the inferior orbital fissure and to the base of the skull through the base of the pterygoid process.

Follow-up after surgery to detect recurrence. Androgen receptor, juvenile angiofiborma, nasopharyngeal angiofibroma. Head Neck, 19pp. As this tumor is aggressive and expansile, it invades adjacent structures causing further symptoms.

The most significant risk is blindness, for patients with occlusion of the ophthalmic or middle cerebral artery through the collateral circulation. This supports the hypothesis that the vascular endothelial cells may become postembryonic undifferentiated mesenchymal cells and can be induced into other mesenchymal nonhemopoitic cell phenotypes.



Juvenile nasopharyngeal angiofibroma

However, open surgery through limited approaches facial translocation by degloving and subtemporal preauricular approach continues to play an important role in advanced tumours, without causing significant morbidity or major aesthetic sequelae. Endoscopic Laser-assisted excision of juvenile nasopharyngeal angiofibromas. Surgical excision was done with moderate intraoperative bleeding. At the time of diagnosis, the mass classically involves the pterygopalatine fossa.

Juvenile nasopharyngeal angiofibroma

They develop at a slightly older age and occur more commonly in women. However these patients had the following characteristics, the number two is the youngest patient in the study group, which for some authors is related to increased tumor aggressiveness.

These figures are similar to those described in the literature. Immunohistochemical and electron microscopical characterization of stromal cells in nasopharyngeal angiofibromas.

The surgical approach can be made through open, as the transpalatal, transmaxillary, rhinotomy lateral mid-facial angiofibrooma osteotomy and Le Fort type I 3,6,8,9,16, The five patients in this study underwent endoscopic resection four days after arteriography with embolization. Accessed December 31st, However, complete resection of the tumour requires sufficient surgical exposure. The authors have no conflicts of interest to declare.

The infratemporal fossa approach for nasopharyngeal tumors.

Treatment trends in patients during 40 years. Squamous-cell carcinoma Adenocarcinoma Mucinous cystadenocarcinoma Large-cell lung carcinoma Rhabdoid carcinoma Sarcomatoid carcinoma Carcinoid Salivary gland—like carcinoma Adenosquamous carcinoma Papillary adenocarcinoma Giant-cell carcinoma. Thank you for updating your details.


This patient is awaiting examination for staging and subsequent treatment planning. Efforts to determine the pathogenesis of the tumor have been done by studying the expression of various growth factors and oncogenes such as C-KIT and C-MYC.

On palpation, the swelling was firm and nontender. External carotid clamping has been shown to assist in hemostasis of the tumor.

Abstract Juvenile nasopharyngeal angiofibroma JNA is a rare benign tumor arising predominantly in the nasopharynx of juvebil males. Arch Pathol Lab Med ; Tumors may invade the anterior fossa through the ethmoid and sphenoid sinuses, being more frequent in the middle fossa and remaining jvenil 8,9, We performed a columellar incision intersects similar to access to the perichondrium of anglofibroma septum septoplasty nasoangiofibroma the opposite side.

Direct intratumoral embolization of juvenile angiofibroma. Some authors link the administration of RT with the appearance of facial hypotrophy and cases of JNA becoming malignant. Postoperative coronal C and axial D CT scan of the same patient, after tumour resection through endoscopic sinonasal surgery. Tumour extension produces rhinosinusal symptoms and facial swelling. The first mention of an endoscopic resection date of Longer duration of surgery is associated with greater changes in body homeostasis due to surgical trauma.

Over the past 10 years the treatment of this disease has been discussed with the aim of designing a management protocol.