La lentiginosis unilateral parcial es un trastorno pigmentario poco común, caracterizado por la agrupación unilateral de numerosas manchas marrones que . Partial unilateral lentiginosis (PUL) is an unusual pigmentary disorder characterized by numerous lentigines grouped within an area of normal. Partial unilateral lentiginosis colocalized with naevus depigmentosus. S. I. In. Department of Dermatology, Ajou University School of Medicine.

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No family members have similar lesions. Partial unilateral lentiginosis with ipsilateral Lisch nodules and axillary freckling.

Melanocytic Nevi – Partial Unilateral Lentiginosis

These cytokines activate melanocytes and increase melanin synthesis in the melanosomes, therefore causing PIH [ 101112 ]. YAG laser with low pulse energy. Article in Pediatr Dermatol Micali G et al.

Clinical manifestations and treatment response of the patient. Please type a message to the paper’s authors to explain your need for the paper. Also, other cases of PUL, coexisting with ipsilateral Lisch nodules, axillary freckling, or skeletal alterations, seem to suggest that many cases of PUL represent a particular form of segmental NF1 lacking neurofibromas, i.

Case Report A year-old female presented with a history of unilateral hyperpigmented macules on her left cheek and periorbital area since early childhood. She had a melanoma in the left nose wing, which had been excised a year before Figures 1 and 2. Case Report Open Access. Also, a few cases of PUL were associated with abnormalities of the central nervous system, including mental retardation and ipsilateral cerebrovascular abnormalities with focal epilepsy, leading to the idea that both conditions resulted from a common developmental problem of the neural crest [ 7 ].

If the distribution of the lesion is limited to a single dermatome, it may be confused with nevus spilus, also known as lentiginous nevus or zosteriform nevus [ 45 ]. Trattner A,Metzker A Partial unilateral lentiginosis. Physical examination revealed multiple brown macules measuring 1. YAG laser may achieve good cosmetic results in the treatment of PUL with a very safe and effective profile. There is a hypothesis that LUP may represent a mosaicism of a generalized form of lentiginosis with melanocytic proliferation likewise the LEOPARD syndromeforming real lentigos simplex and eventually may be subject to malignant transformation [ 2 ].


SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal’s impact. The mechanism of low-fluence 1,nm QS Nd: Journal List Case Rep Dermatol v. Then, press proceed to send the authors a message.

By checking this box you hereby agree to hold Perri Dermatology, PLLC Inc, its doctors and affiliates, harmless from any hacking or any other unauthorized use oentiginosis your personal information by outside parties. If appropriate measures are taken to monitor patient response during and after the procedure, low-fluence 1,nm QS Nd: J Am Acad Dermatol Partial unilateral lentiginosis with associated developmental abnormalities. Human fibroblasts secrete several melanogenic cytokines, such as bFGF, HGF, and SCF, when they are rapidly growing or during inflammation, which suggests the possibility that overexpression of these cytokines by dermal fibroblasts may activate melanocytes in the overlying epidermis [ 13 ].

Partial Unilateral Lentiginoses | OMICS International

Patient photos were taken at baseline Fig. J Am AcadDermatol 8: No guarantees or warranties lebtiginosis made regarding any of the information contained herein.

InMcKelway was the first author to study a case of a patient with unilateral distribution of lentigines, but Pickering was first to introduce the term partial unilateral lentigines in [ 59 ].

When affecting the lips, the Peutz-Jeghers syndrome should be investigated [ 11 ]. No claim or opinion on these pages is intended to be medical advice or to replace a one-on-one relationship with a qualified health care professional. Nevus spilus manifests clinically as a grouping of numerous lenticular elements, brownish macule or papule on a uniform hyperpigmented background, with diameters between 1 and 20 cm subject to appear both in childhood as in adulthood [ lsntiginosis ].

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Habit-associated salivary pH changes in oral submucous fibrosis-A controlled cross-sectional study. By checking this box you hereby agree to hold Perri Dermatology, its doctors and affiliates, harmless from any hacking or any other unauthorized use of your personal information by outside parties.

Over the last few years, the 1,nm Q-switched neodymium-doped yttrium aluminum garnet QS Nd: Treatments lentjginosis conventional laser methods are sometimes unklateral due to common side effects, such as postinflammatory hyperpigmentation PIHscarring, and recurrences.

J Eur AcadDermatolVenereol PUL can appear anywhere on the body, including the face, neck, trunk, and extremities [ 2 ]. Under the clinical impression of facial PUL, the patient was subjected to 10 laser treatment sessions using a 1,nm QS Nd: A 9-year-old Taiwanese girl had an unusual combination of multiple lentigines clustered on her left face, 3 cafe-au-lait spots on her left arm and ipsilateral axillary freckling. In Partial Unilateral Lentiginosis, small brown melanocytic nevi develop on one half of the body.

Continuing navigation will be considered as acceptance of this use. Because mature melanosomes accumulate in the dendrites of lentiginosi, the selective photothermolytic effect of the laser can be focused intensively on dendrites. Br J Dermatol Sign Unilaterql Join Now. J Electron Microsc Tokyo ;