Diffuse axonal injury (DAI) is a brain injury in which extensive lesions in white matter tracts occur over a widespread area. DAI is one of the most common and. lesión axonal difusa. Artículo. Facial emotion recognition in patients with focal and diffuse axonal injury. Autor/es: Yassin W, Callahan BL, Ubukata S, Sugihara G. Toda lesión en la cabeza puede causar una lesión cerebral traumática. Existen daño a los nervios (lesión axonal difusa): se deriva de una fuerza cortante o.

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Delayed presentation of diffuse axonal injury: A sequence such as gradient echo that accentuates the susceptibility artifact arising from blood products must be performed in order to recognize small petechial hemorrhages. Prediction of recovery from a post-traumatic coma state by diffusion-weighted imaging DWI in patients with diffuse axonal injury. Any patient with a closed head injury who experiences extensive loss of consciousness and neurological deficits warrants neuroimaging.

Besides mechanical breaking of the axonal cytoskeleton, DAI pathology also includes secondary physiological changes such as interrupted axonal transport, progressive swellings and degeneration. Intraventricular hemorrhage on initial computed tomography as marker of diffuse axonal injury axohal traumatic brain injury. Lesiones cerradas de cabeza: The axial gradient-echo sequence on the right confirms axoonal in the right frontal lobe from diffuse axonal injury DAI.

Magnetic resonance imaging MRI is the preferred examination for DAI particularly with gradient-echo sequencesalthough CT scanning may demonstrate diufsa suggestive of DAI and is more practical and available. Diffusion-weighted MR imaging of the brain.

Diffuse axonal injury | Radiology Reference Article |

MRI is the modality of choice for assessing suspected diffuse lesipn injury even in patients with entirely normal CT of the brain Actual complete tearing of the axons is only seen in severe cases. Over the first few days, the degree of surrounding oedema will typically increase, although by 3-months post-injury FLAIR changes will have largely resolved 7.


In Grade II, damage found in Grade I is present in addition to focal abnormalities, especially in the corpus callosum.

Unfortunately little can be done for patients with diffuse axonal injury other than trying to minimise secondary damage caused by cerebral oedema, dirusa, etc. Print this section Print the entire contents of Print the entire contents of article. In Grade I, widespread axonal damage is present but no focal abnormalities are seen.

Longitudinal study of the diffusion tensor imaging properties of the corpus callosum in acute and chronic diffuse axonal injury.

As such, it is usually a safe assumption that if a couple of small haemorrhagic lesions are visible on CT, the degree of damage is much greater. Susceptibility weighted image SWI of diffuse axonal injury in trauma at 1. As such the diagnosis is often not suspected until later when patients fail to recover neurologically as expected.

Intracranial hemorrhage Intra-axial Intraparenchymal hemorrhage Intraventricular hemorrhage Extra-axial Subdural hematoma Epidural hematoma Subarachnoid hemorrhage Brain herniation Cerebral contusion Cerebral laceration Concussion Post-concussion lesoon Second-impact syndrome Dementia pugilistica Chronic traumatic encephalopathy Diffuse axonal injury Abusive head trauma Penetrating head injury. Case 6 Case 6.

lesión axonal difusa

Case 5 Case 5. Figure 1 Figure 1. Clinical utility of diffusion tensor imaging for evaluating patients with diffuse axonal injury and cognitive disorders in the chronic stage. MR imaging of head trauma: Dlfusa sequences can reveal hyperintensities in areas of axonal injury. Post-traumatic coma may last a considerable time and is often attributed to coexistent more visible injury e. Share cases and questions with Physicians on Medscape consult.


Cifusa injury has more microscopic injury than macroscopic injury and is difficult to detect with CT and MRI, but its presence can be inferred when small bleeds are visible in the corpus callosum or the cerebral cortex. Evidence for enduring changes in axolemmal permeability with associated cytoskeletal change.

In addition, MRI is difficult to perform on patients who have claustrophobia and on ventilator-dependent patients. What would you like to print? Chin Med J Engl. Se puede pedir al paciente que comente cuentos o narraciones y los puntos de vista de axonak personajes.

Non-contrast CT of the brain is routine in patients presenting with head injuries. Diffuse axonal injury after traumatic cerebral microbleeds: Axonall Lesion s in Traumatic brain injury: In contrast, SWI changes will usually take longer to resolve, although by months post-injury there will have been substantial resolution 7.

Wang and colleagues [ 12 ] suggested CT scan criteria using the presence of one or more small intraparenchymal hemorrhages less than 2 cm in diameter located in the cerebral axona, intraventricular hemorrhage, hemorrhage in the corpus callosum, small focal areas of hemorrhage less than 2 cm in diameter adjacent to the third ventricle, and brainstem hemorrhage as characteristic of DAIs.