MAERUA ANGOLENSIS PDF
Maerua angolensis DC. [family CAPPARACEAE]. Herbarium. Royal Botanic Gardens, Kew (K). Collection. Useful Plants of West Tropical Africa. Resource Type. Maerua angolensis is widely distributed in continental tropical Africa but is absent in some countries with a high rainfall. It is also present in the. Abubakar, M.S., Musa, A.M., Ahmed, A. & Hussaini, I.M., The perception and practice of traditional medicine in the treatment of cancers and inflammations .
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This page was last modified on 25 Octoberat It is not suitable for firewood but the wood is used to make charcoal. Maerua angolensis Prelude Medicinal Plants Database x – k – jpg www. Although the influence of oxidative stress as a cause or consequence of epilepsy is still debated, it is agreed as common knowledge that the production of free radicals plays a role in the pathogenesis of epilepsy [ 5 ].
An appreciable number of current antiepileptic agents modulate receptor or enhance the response of this receptor to the gamma amino butyric acid GABA.
Coadministration of pentylenetetrazole after pretreatment with subeffective doses of L -arginine or sildenafil reversed the anticonvulsant effects of MAE.
To identify the potential antioxidant benefit, the extract might have on the prognosis in the PTZ-induced seizure in the rat model an assessment of in vitro protection against free radicals and an in vivo assessment of the oxidative state and markers after PTZ-induced seizures were assessed. Maerua angolensis is a 10m tall, occasionally deciduous tree of the Capparaceae or caper family, often growing on termitaria and in thickets fringing seasonal watercourses, up to m.
Maerua angolensis Prelude Medicinal Plants Database x – 37k – jpg www. The superoxide anion radicals were generated in 3. National Museums of Kenya, Nairobi, Kenya.
Kirkia 10 1 Page Thus, the need to source for clinically efficacious and safer antiepileptic drugs AEDs with such improved mechanisms and clinical benefit is still valid. De Vries, and M. Rats were observed for latency to and duration of myoclonic seizures and additionally the level of protection against oxidant markers and products was assessed in vitro and in vivo.
It is based on the ability of the enzyme source to break down H 2 O 2.
Maerua angolensis Images – Useful Tropical Plants
The 4 calyx segments recurve mafrua opening, and the base is fringed with hairs. Navigation menu Personal tools Log in Request account. The wood is usually small-sized and used for mortars, tool handles, small furniture and posts.
Insects associated with this species: In oxidative stress, free radicals such as superoxide anions are generated and overwhelm the normal protective mechanisms and consequently contribute to the detrimental effects jaerua brain tissue. Comparatively high production of reactive oxygen species and ironically low antioxidant capacity make it exceptionally vulnerable to neuronal and glial cell damage, which in turn can contribute to the initiation and angolensi of several central nervous disorders including epilepsy [ 3 ].
However, rats pretreated with MAE or diazepam showed no reduction in catalase activity Figures 8 a and 8 b. In Tanzania the powdered leaves are used as fish-poison. To receive news and merua updates for Evidence-Based Complementary and Alternative Medicine, enter your email address in the box below. The reaction was started by adding 0. View at Google Scholar G. The fragrant, pincushion-like flowers are without petals and are produced in abundance at the beginning of the rainy season.
Maerua angolensis Images
In this study, acute administration of MAE and diazepam exhibited anticonvulsant activity against PTZ-induced seizures by significantly delaying the occurrence of clonic seizures. Elsewhere in Africa wounds, abscesses, sores and ulcers are treated with leaves or pulped leaves as a angolwnsis, and leaf sap is sprinkled on or rubbed in with ground fruit.
Capparaceae Flora Zambesiaca 1 1 Pages – Control experiment contained only methanol and DPPH free radical. Flowers axillary, solitary, in terminal spikes or in clusters on small lateral spurs, without petals, stamens numerous and long, white fading to yellow. Taken together, the data support a role for MAE in attenuation of neuronal damage after seizure attacks, in part at least, by inhibition of oxidative stress injuries.
PTZ blocks GABA-mediated Cl — influx through an allosteric interaction in the Cl — channel, thus leading to induction of convulsions in animals [ 2324 ]. The superoxide anion scavenging activity was measured as described by Robak and Gryglewski [ 13 ].
The species is variable as regards pubescence, ranging from angllensis glabrous to pubescent on stems and leaves. There are 1 news article citations related to Maerua angolensis DC. Articles with ‘species’ microformats. In PTZ-induced seizures, NO levels are elevated and hence NOs inhibitors have been found to suppress seizure angolensjs including latency to convulsions [ 22629 ]. Chemicals and Drugs Sildenafil was obtained from Pfizer Inc.
The stem bark of Maerua angolensis DC. In recent times, quite a number of Ghanaian plants have been shown to exhibit diverse central nervous system activities ranging from anxiolytic activity to antidepressant and anticonvulsant activity [ 1117 — 19 ].
Brain superoxide dismutase activity was measured based on the ability of SOD to inhibit autoxidation of adrenaline to adrenochrome. Similar results were obtained for diazepam. Experimental studies suggest that an imbalance in the oxidative state of brain angolenais cells is a contributing factor to the induction and propagation of epilepsy.